Welcome to the Genome Center

Established in 2003, the UC Davis Genome Center uses state-of-art-technologies to understand how the heritable genetic information of diverse organisms function in health and disease. The combination of cutting-edge research facilities, diverse service cores, and talented staff make the Genome Center a world class facility for genomics research and training.

Research that makes a difference

A sample of questions being addressed by the UC Davis Genome Center faculty and their collaborators:

  • How do variations in the human genome affect the risks of diseases such as cancer, coronary artery disease, and autism?
  • Do infection, diet, or stress serve as environmental triggers of Type 1 diabetes?
  • What novel, useful organisms will be discovered by sequencing microbes from extreme environments?
  • Can characterization of the small chemicals in algae lead to new biofuels?
  • How can we control diseases of important food crops?
  • How can plants be modified to increase their productivity and quality?
  • What changes can we make to proteins to enhance their performance?
  • Can we model and predict life’s basic processes?
  • How can we glean useful information from vast datasets?

News highlights

Here are just some of the recent highlights involving people and projects at the Genome Center Please see the news page for a full list of all news items.

Updates from the DNA Technologies and Expression Analysis Cores

April 14, 2015

The following announcements are taken from the April Newsletter from the DNA Technologies and Expression Analysis Core Facilities. Read the newsletter for full details.

Latest Generation Illumina HiSeq 3000 Sequencer now available

The Genome Center has acquired a HiSeq 3000 sequencer that provides faster sequencing at significantly reduced per-base-costs. The new sequencer is already delivered and will ... Read more...

The 2015 David L. Weaver Endowed Lecture will be given by Professor Stephen Quake

April 9, 2015

Every year, the Genome Center remembers the life and scientific achievements of David L. Weaver by hosting an Endowed Lecture in his honor. This series of lectures has seen many distinguished scientists come to Davis to present highly-regarded talks concerning their work.

This year’s lecture will be given by Professor Stephen Quake ... Read more...

Ian Korf featured in Nature commentary regarding Bioinformatics Service Cores

April 8, 2015

A new commentary article in this week’s edition of  Nature includes some quotes from Ian Korf, Associate Director of Bioinformatics at the Genome Center who also serves as the Interim Director of the UC Davis Bioinformatics Core. The article discusses the issues relating to providing bioinformatics training and the need for good career paths for ... Read more...

Professor Pam Ronald interviewed for the ‘People Behind the Science’ Podcast

March 26, 2015

People Behind the Science podcast

The latest episode of the People Behind the Science podcast features the Genome Center’s Pam Ronald. The podcast host, Dr. Marie McNeely, speaks to Pam about her work, her role models, and her life outside of science. You can listen to the ... Read more...

Professor Pamela Ronald speaks at TED 2015 conference

March 23, 2015

TED wordmark

Genome Center member Pamela Ronald was invited to speak at this year’s TED conference, where she spoke about the use of genetic engineering in plants to help improve food security and combat disease.

For over three decades, TED conferences have brought together some of the most thoughtful and ... Read more...

Upcoming Talks and Events

Events on April 23, 2015
The 2015 David L. Weaver Endowed Lecture: Professor Stephen Quake — “Single Cell Genomics”
Starts: 3:00 pm
Ends: April 23, 2015 - 4:00 pm
Location: Auditorium (room 1005), Genome and Biomedical Sciences Facility, UC Davis
Description: For more details, see: http://genomecenter.ucdavis.edu/outreach-giving/david-l-weaver-endowed-lecture/

Stephen Quake is a Professor of Biomedical Engineering at Stanford University and a Howard Hughes Medical Institute Investigator. His research focuses on topics that lie at the nexus of physics, biology, and biotechnology and his research group pioneered the development of Microfluidic Large Scale Integration (mLSI), demonstrating the first integrated microfluidic devices with thousands of mechanical valves. This technology is helping to pave the way for large scale automation of biology at the nanoliter scale, and he and his students have been exploring applications of lab-on-a-chip technology in functional genomics, genetic analysis, and structural biology. Professor Quake is also active in the field of single molecule biophysics.

Refreshments will be provided after the lecture.
Events on April 28, 2015
Seminar — Dr. Li Fang — A New Paradigm In The Detection And Measurement Of Tissue Based Biomarkers
Starts: 12:00 pm
Ends: April 28, 2015 - 1:00 pm
Location: GBSF Auditorium (room 1005)
Description: Dr. Li Fang from Advanced Cell Diagnostics will present the high sensitivity in situ hybridization technology RNAscope.

Lunch will be provided
Events on May 4, 2015
Workshop — mRNAseq for non-model organisms
Starts: 12:00 am
Ends: May 6, 2015 - 12:00 am
Description: This workshop is open to everyone, including graduate students, postdocs, staff, faculty, and community members. We have extra space for UC Davis VetMed affiliates; contact the lead instructor if you are an SVM affiliate. (These spaces will be released to the wait list on Monday, April 27th.)

This two-day hands-on workshop will introduce biologists to doing de novo transcriptome analysis with khmer and Trinity. The primary focus will be on non-model organisms - organisms with no reference genome and poor gene annotations. The workshop will be eukaryote-focused (poly-A mRNA/large genomes/genes with introns).

We will be analyzing a stock data set, and we will be using the Amazon cloud.

More details here: http://dib-training.readthedocs.org/en/pub/2015-05-04-mRNAseq-nonmodel.html